Rocco & Roxie Stain and Odor Eliminator: Amazon’s #1 Dog Stain Remover

Updated: Jan. 23, 2024

Say goodbye to pet stains, forever with Rocco & Roxie pet stain removing products.

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I have a one-year old dog. And though Louie is housebroken and has very good manners, any pet owner knows that if you have pets, you have pet messes.

My cleaning closet holds three pet stain removers, but none of them really work. One pet cleaner with a built-in scrub brush even ruined the fibers of a wool carpet without completely pulling up a urine stain.

I recently learned about Rocco & Roxie stain and odor eliminator in an article on removing pet urine from carpets right here on Family Handyman. The best-selling product of its kind on Amazon with more than 75,000 five-star reviews, the Rocco & Roxie tagline says, “If it’s gross, it’s gone.” And they offer money-back guarantee. I had to try it.

Naturally, it didn’t take long for Louie to make a mess and test it.

What is Rocco & Roxie?

Rocco & Roxie Supply Co. is a family owned and operated business inspired by Rocco (a Labradoodle) and Roxie (a Tabby cat). The line of superior pet products focuses on quality, safety and the understanding that pets are part of the family.

Rocco & Roxie offers everything from treats to toys to dog shampoo and supplements. For this review, we focused on two of their best-selling pet stain removers: Professional Strength Stain and Odor Eliminator and the Oxy Stain Remover. These are great products for getting cat pee out of clothes and other materials.

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Rocco & Roxie Product Features

The Professional Strength Stain and Odor Eliminator and the Oxy Stain Remover both come in standard-size cleaning spray bottles, and while they’re professional-strength cleaners, they are both people- and pet-safe. The multi-surface spray is chlorine free and color safe—no hazardous residue will be left behind.

The small-business-made formula is bio-enzymatic, meaning it penetrates and gets deep down to eliminate the mess. The natural enzymes in the spray are activated on contact to totally eliminate pet odors.

How We Tested It

 Rocco & Roxie Oxy Stain Remover next to a stain Megan Wood/Family Handyman

I received the two products about three days before it happened. I pulled back my white sheets to make the bed and discovered … dog urine. Or was it liquid feces? Possibly dog vomit? Whatever it was, it happened while I was in the shower, and it was disgusting.

I ran to the cleaning closet and grabbed the Rocco & Roxie cleaners. This was a real life pet stain remover test.

Rocco & Roxie Professional Strength Stain and Odor Eliminator

The first thing I did after I discovered the mess was strip the sheets off the bed. Of course, the dog mess had soaked through the sheets and onto my memory foam mattress. Gross! (More on how I tackled that mess with the Oxy Stain Remover review below.)

The mess on the sheets had partially set, so I sprayed the linens with Stain and Odor Eliminator first. Dog owners know that once a dog has “marked” somewhere in the house, they often return to that spot to make additional messes. It’s gross, but it’s dog behavior. That’s why it’s so important to not only remove dog urine and feces stains, but to completely eliminate the bad dog smell so that even a canine’s strong nose can’t whiff it out for a second marking.

Rocco & Roxie Stain and Odor Eliminator contains natural enzymatic bacteria that are activated on contact with stains and odors. The solution feeds on ammonia crystals and organic matter until they’re completely eliminated. What does the solution smell like? Sort of a mix of bubble gum and essential oils, but the scent doesn’t linger.

To clean my sheets of dog mess odors and stains, I shook the bottle and liberally sprayed the affected area. Then I let it sit for 30 minutes and blotted again. By the time I came back to blot my sheets for a second time, the brown stain had completely lifted!

I tossed the sheets in the washing machine with laundry detergent. After the cycle finished, the stain was invisible and the sheets smelled like freshly washed laundry. My white sheets were saved.


  • It works! Quickly removes stains and odors caused by pet messes old and new
  • Good on carpets, hardwood floors, furniture, clothes, litter boxes, kennels, carriers—anywhere pets make a mess
  • Certified gentle and safe to use around pets and children
  • 100% satisfaction guarantee


  • More expensive than competing pet stain cleaners

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Rocco & Roxie Oxy Stain Remover

using Rocco & Roxie Oxy Stain Remover on a couchvia merchant

You can’t throw a mattress in the washing machine, and one bad stain is enough to ruin it. I cringed at the thought of replacing an expensive necessity. But I stayed calm and followed the directions on the Rocco & Roxie Oxy Stain Remover.

I simply sprayed the solution onto the stain, then headed for the kitchen to grab a white towel to dab up the product. By the time I returned to the scene of the crime, I couldn’t see the stain! I had to feel the mattress for a damp spot to find it. That’s a cleaning miracle.

I dabbed up the remaining solution, then opened the window so the mattress would dry faster. An hour later, the spot was dry and there was no evidence of a stain. Yes, I smelled the mattress and it smelled fresh, with the slightest hint of a citrusy cleaning product.

Activated oxygen is the secret to this pet stain remover. Lots of people even use this product on laundry and carpet stains unrelated to pets. Red wine, fruit stains and chocolate are no match for Rocco & Roxie Oxy Stain Remover.

Impressed with the quick removal of the mattress stain, I remembered the weeks-old dog urine stain I couldn’t get out of a wool carpet. A few spritzes of Oxy Stain Remover and the yellow tinge came right up. (Always do a spot test on colored fabrics.)


  • It works! Removes even set-in stains from multiple fabrics and surfaces
  • Light citrus smell is pleasant and not overpowering
  • Safe to use around pets and kids


  • More expensive than competing pet stain cleaners

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What Other Reviewers Had to Say

I’m not the only one who has seen success with Rocco & Roxie Stain and Odor Eliminator. Amazon is filled with multi-paragraph, five-star reviews from people who foster multiple pets, breed dogs, or have chiseled hardened cat urine off floors. All of them love this product. Some of the reviews have more than 9,000 likes. And the before and after photos are amazing. Pet owners have blue light evidence!

Benjamin Poon, a verified Amazon says, “TLDR: BUY THIS. It’s worth the $20 to not have to smell or look at your dogs’ pee, poo, vomit and stains in your house. Safe on virtually all porous surfaces — including bedding and couches. MAGIC IN A BOTTLE. The end.”

Amazon reviewers also love Rocco & Roxie Oxy Stain Remover, but without the same cult following as the Rocco & Roxie Stain and Odor Eliminator. The Oxy Stain Remover has more than 1,500 five-star Amazon reviews, and some inspiring before and after photos featuring nasty yellow urine stains. Parents also use this product for human potty training accidents.

Verified Amazon purchaser Elaine P. says, “My four-legged niece peed on my family room basement floor causing a huge dark spot. I tried Woolite and baking soda everything and it still showed on my light brown carpet. This happened over a year ago so I thought I’d try this cleaner because I just love Rocco & Roxie and the stain is gone!!! Can’t even tell there was ever anything there!! Best stain remover ever, can’t wait to try it on ink or any other home mishap!!”

Final Verdict

 Rocco & Roxie Oxy Stain Remover via merchant

I threw my other pet stain removers in the garbage. Yes, Rocco & Roxie might cost a little more than competing brands. But this stuff actually works, and saved me from replacing a mattress. From now on, I’m a Rocco & Roxie Supply Co. pet owner.

Want to try Rocco & Roxie pet stain removing products yourself? They’re available on Amazon and Chewy, and at Target and Walmart.

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