Insulating foam is great for sealing out drafts, but not so great for keeping out mice and other pests that can chew their way through in a heartbeat. I had a problem with mice chewing through the weather stripping near the bottom of my garage door (see photo). I sprayed a glob of DAP Products’ Touch ’n Foam Mouse Shield behind each entry point last fall. It was amazing! Not one foam barrier was breached. You can get it for about $8 and up online.
Great Stuff Pestblock, another pest-deterring foam sealant, contains an ingredient that tastes bad to critters. It’s available at home centers for about $7.