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6 Things to Absolutely Always Buy at Big-Box Stores (and 4 to Get at Retail)

Need prescription drugs? Cleaning supplies? Here's when warehouse club prices are worth it, and when they're probably not.

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Pills close up and colorful blister packsPavel Kubarkov/Shutterstock

Buy: Prescription Drugs

When Consumer Reports called more than 200 pharmacies nationwide for prices on a month’s supply of commonly prescribed drugs, it found a 450 percent difference in cost between the highest- and lowest-priced stores. Drugs at big-box store pharmacies were much cheaper than those at many drugstore chains, especially if you opt for generics. Plus, you don’t need a membership—warehouse pharmacies are required by law to remain open to the public. Don’t miss these Costco shopping tips that will save you tons of money.

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Macro close up toasted oats grain breakfast cereal. Multiple cicle shaped Os in white bowlBravoKiloVideo/Shutterstock

Buy: Cereal

Stock up on the big-box store version that comes in two large bags to a pack. You can save 60 percent on favorites such as Froot Loops and Honey Nut Cheerios by buying in bulk. Even organic cereals can cost 25 percent less at warehouse clubs. Check out these bizarre things you never knew you could get at Costco.

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dry dog food in bulk close up279photo Studio/Shutterstock

Buy: Pet Supplies

Certain brands of dog food can be up to 60 percent less expensive at a big-box store compared with popular pet stores, so it pays to comparison shop for your pooch’s favorite kibble. Here are the things you should only buy at Trader Joes.

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Close-up of wine bottles in supermarketwavebreakmedia/Shutterstock

Buy: Liquor

Some warehouse clubs have partnerships with vineyards that award them deeply discounted prices for bulk purchases—which means you can save about 30 percent on certain wines. Warehouse store brands of other liquors, like Kirkland vodka, can cost nearly 40 percent less than premium brands like Grey Goose. Depending on your state laws, you may not need a membership to purchase liquor at a club store. Since you’re a fan of shopping at big-box stores, you won’t want to miss the secret code behind Costco’s prices.

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Abstract blurred Men fashion jeans shirt on wood clothes hangerSurasak Ch/Shutterstock

Buy: Men’s Dress Shirts

Clothing is often deeply discounted but still of good quality at a big-box store. We’ve seen men’s dress shirts at a warehouse store for 30 percent less than popular retailers. Plus: Did you know you could get these services at Walmart?

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Charcoal close upBelkaG/Shutterstock

Buy: Charcoal

Though it comes in large quantities—typically two 20-pound bags packaged together rather than a single five- to ten- pound bag—charcoal is usually less expensive at the big-box store than at supermarkets. During grilling season, you’re likely to use it up quickly. Even if you don’t, charcoal has an indefinite shelf life if stored in a cool, dry place.

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Close up of multicolor capsules blister packaging backgroundi viewfinder/Shutterstock

Skip: Over-The-Counter-Medicine

You probably don’t use OTC medications every day, so that jumbo bottle of pain reliever from the big-box store might expire before you can finish it. Choose a regular-size bottle of a generic brand at your local drugstore or supermarket. Don’t miss these other things you should never buy at Costco.

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Cleaning sponges isolated on white backgroundNik Merkulov/Shutterstock

Skip: Cleaning Supplies

Liquid cleaners typically lose some effectiveness after six months to a year (certain powders may have an indefinite shelf life if stored in a cool, dry place). Unless you have a large family, purchase household supplies like window cleaner, dish detergent, laundry soap, and bleach in regular-size containers at retail stores.

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Composition with paper towel rolls, isolated on whitethodonal88/Shutterstock

Skip: Paper Goods

Common household items go on sale so often that supermarket discounts may be deeper than big-box store price cuts. Pairing store sales with manufacturer coupons can dramatically shrink your bill.

Plus: These 10 things are actually cheaper at Walmart than Amazon.

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Fresh grilled meat. Grilled beef steak medium rare on cutting board. Close up.nadianb/Shutterstock

Skip: Meat

Supermarkets rotate sales on various meats so shoppers will come for cheap prices and then buy more profitable packaged goods. Manager markdowns are also often available when meat nears its expiration date. Next, check out the secrets Costco employees aren’t telling you.

Sources: Andrea Woroch, a consumer savings expert; Jeanette Pavini, a savings expert at coupons.com; Trae Bodge, senior lifestyle editor for the Real Deal blog at retailmenot.com; consumerreports.org; kiplinger.com; goodhousekeeping.com; today.com; womansday.com; thecouponproject.com; and thedailymeal.com

Originally Published in Reader's Digest